Chinese Journal of Tissue Engineering Research ›› 2012, Vol. 16 ›› Issue (34): 6389-6392.doi: 10.3969/j.issn. 2095-4344.2012.34. 024

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Research progress of chitosan hydrogel in the field of biomedical materials

Qin Ying-zhe, Lin Qiang   

  1. Applied Arts and Sciences Institute of Beijing Union University, Beijing 100191, China
  • Received:2011-12-28 Revised:2012-03-05 Online:2012-08-19 Published:2012-08-19
  • Contact: Lin Qiang, Doctor, Master’s supervisor, Professor, Applied Arts and Sciences Institute of Beijing Union University, Beijing 100191, China
  • About author:Qin Ying-zhe★, Studying for master’s degree, Applied Arts and Sciences Institute of Beijing Union University, Beijing 100191, China qyz19861024@ 126.com

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Abstract:

BACKGROUND: Chitosan hydrogel exhibits several favorable biological properties such as low toxicity, good biocompatibility and biodegradation.
OBJECTIVE: To review the applications of chitosan hydrogel in controlled drug delivery, tissue engineering, and biosensors.
METHODS: The first author searched Springer electronic journals and CNKI database to retrieve the literatures about chitosan hydrogel used in biomedical materials from 2002 to 2011.
RESULTS AND CONCLUSION: Chitosan hydrogel is sensitive to temperature or pH, but has little influence on drugs and proteins. The physical properties of chitosan hydrogen can be improved and enhanced by modification or/and combination with other polymer composites. To date, chitosan hydrogel has been widely used in controlled drug delivery, tissue engineering, biosensors and other biomedical fields. In view of its great biological potential, chitosan hydrogen need to be further studied.

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